Opus Genetics Completes Dosing in Cohort 2 of Phase 1/2 Clinical Trial of OPGx-BEST1
Opus Genetics has finished dosing the second cohort in its BIRD-1 Phase 1/2 clinical trial evaluating OPGx-BEST1 for the treatment of inherited retinal diseases.
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Opus Genetics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)
Opus Genetics, Inc. announced that its Compensation Committee approved equity awards for ten new non-executive employees as a material inducement to employment.
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Opus Genetics Completes Dosing in Cohort 2 of Phase 1/2 Clinical Trial of OPGx-BEST1 Gene Therapy for Inherited Retinal Diseases
Opus Genetics announced completion of dosing in Cohort 2 of its BIRD-1 Phase 1/2 clinical trial for OPGx-BEST1, a gene therapy for BEST1-related retinal diseases. The higher-dose cohort enrolled 11 participants (exceeding the target of 5) at 4.5 × 10⁹ vg/eye. Topline three-month data is expected in Q1 2027, with potential Phase 3 pivotal trial dosing anticipated in H2 2027. Cohort 1 showed favorable safety and clinically meaningful improvements in visual function across all five participants.
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8-K filing — Opus Genetics, Inc. (IRD)
Filed: 2026-10-21 AccNo: 0001140361-26-040377 Size: 153 KB Item 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers Item 9.01: Financial Statements and Exhibits
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