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Agenus Announces Nature Medicine Publication of Multicenter UNICORN Phase 2 Trial Results
Agenus Inc. announced the peer-reviewed publication of results from the Phase 2 UNICORN trial, which evaluated neoadjuvant botensilimab and balstilimab in patients with resectable colon cancer.
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Colorectal Cancer Market Set for Significant Growth During the Forecast Period (2026–2036), Due to the Emergence of Emerging Targets such as KRAS G12C, NTRK Fusions, and PIK3CA Mutations | DelveInsight
The colorectal cancer market is projected to grow significantly from 2026-2036, driven by rising incidence rates, increased disease awareness, and adoption of targeted therapies and immunotherapies. The market was valued at approximately USD 13 billion in 2025. Key growth drivers include emerging therapies targeting KRAS G12C, NTRK fusions, and PIK3CA mutations, with major pharmaceutical companies launching innovative treatments. The US accounts for the largest market share among the 7 major markets analyzed.
Agenus Reports Positive Phase 2 Results for BOT+BAL in NEOASIS Study at ESMO 2026
Agenus announced that 72% of patients with locally advanced dMMR colon cancer achieved a pathological complete response following six weeks of neoadjuvant treatment with botensilimab and balstilimab.