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Faeth Therapeutics has appointed Adam Schayowitz, Ph.D., MBA, the Executive Vice President and Head of Research and Development at Zymeworks, to its Board of Directors.
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Zymeworks reported new clinical data from its Phase 1 study of ZW191, an antibody-drug conjugate targeting folate receptor alpha, showing anti-tumor activity in platinum-resistant ovarian cancer.
Zymeworks has partnered with Roche to develop ZW209, a trispecific T-cell engager targeting DLL3, in a deal potentially worth over $800 million.
Zymeworks announced a global license and collaboration agreement with Roche for ZW209, a trispecific T cell engager targeting DLL3. Zymeworks will receive $55 million upfront and $40 million upon Phase 1b initiation, with potential for up to $718 million in additional milestone payments and tiered royalties on future net sales. Zymeworks will conduct the Phase 1a trial while Roche funds it and handles subsequent development and commercialization.